G10R (p.Gly10Arg) variant of NR3C1 (Glucocorticoid receptor)
G10R (p.Gly10Arg) in NR3C1 (Glucocorticoid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G10R (p.Gly10Arg) variant details
- p.Gly10Arg
- TOPMed rs1182025204
- gnomAD rs1182025204
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.18
- CADD 4.09
- PolyPhen-2 0.07
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- NR3C1 Zinc finger, nuclear hormone receptor-type domain domainome 1.0: score -0.272