S10F (p.Ser10Phe) variant of NPR1 (P16066)
S10F (p.Ser10Phe) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S10F (p.Ser10Phe) variant details
- p.Ser10Phe
- TOPMed rs1669683617
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.24
- CADD 18.40
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available