R6S (p.Arg6Ser) variant of NPR1 (P16066)
R6S (p.Arg6Ser) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R6S (p.Arg6Ser) variant details
- p.Arg6Ser
- 1000Genomes rs13305996
- ExAC rs13305996
- TOPMed rs13305996
- gnomAD rs13305996
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.12
- CADD 14.90
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available