R5Q (p.Arg5Gln) variant of NPR1 (P16066)
R5Q (p.Arg5Gln) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R5Q (p.Arg5Gln) variant details
- p.Arg5Gln
- TOPMed rs1489803000
- gnomAD rs1489803000
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.19
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available