R28P (p.Arg28Pro) variant of NPR1 (P16066)
R28P (p.Arg28Pro) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
R28P (p.Arg28Pro) variant details
- p.Arg28Pro
- gnomAD 1-153679191-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.21
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available
- Literature evidence available