R13S (p.Arg13Ser) variant of NPR1 (P16066)
R13S (p.Arg13Ser) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R13S (p.Arg13Ser) variant details
- p.Arg13Ser
- TOPMed rs1001658927
- gnomAD rs1001658927
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.27
- CADD 14.60
- PolyPhen-2 0.09
- SIFT 0.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available