R13P (p.Arg13Pro) variant of NPR1 (P16066)
R13P (p.Arg13Pro) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R13P (p.Arg13Pro) variant details
- p.Arg13Pro
- ExAC rs13305997
- TOPMed rs13305997
- gnomAD rs13305997
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.48
- CADD 15.50
- PolyPhen-2 0.19
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available