R11S (p.Arg11Ser) variant of NPR1 (P16066)
R11S (p.Arg11Ser) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R11S (p.Arg11Ser) variant details
- p.Arg11Ser
- TOPMed rs1417422135
- gnomAD rs1417422135
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.17
- CADD 21.20
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available