R11H (p.Arg11His) variant of NPR1 (P16066)
R11H (p.Arg11His) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R11H (p.Arg11His) variant details
- p.Arg11His
- TOPMed rs904927899
- gnomAD rs904927899
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.23
- CADD 21.10
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available