P4S (p.Pro4Ser) variant of NPR1 (P16066)
P4S (p.Pro4Ser) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P4S (p.Pro4Ser) variant details
- p.Pro4Ser
- TOPMed rs1264744512
- gnomAD rs1264744512
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.21
- CADD 9.86
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available