P22S (p.Pro22Ser) variant of NPR1 (P16066)
P22S (p.Pro22Ser) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P22S (p.Pro22Ser) variant details
- p.Pro22Ser
- gnomAD 1-153679172-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.09
- CADD 9.00
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available