P21Q (p.Pro21Gln) variant of NPR1 (P16066)
P21Q (p.Pro21Gln) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
P21Q (p.Pro21Gln) variant details
- p.Pro21Gln
- gnomAD 1-153679170-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.17
- CADD 10.60
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available