N34S (p.Asn34Ser) variant of NPR1 (P16066)
N34S (p.Asn34Ser) in NPR1 (P16066) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
N34S (p.Asn34Ser) variant details
- p.Asn34Ser
- rs1174456586
- gnomAD rs1174456586
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.08
- CADD 18.40
- PolyPhen-2 0.24
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available