L27F (p.Leu27Phe) variant of NPR1 (P16066)
L27F (p.Leu27Phe) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L27F (p.Leu27Phe) variant details
- p.Leu27Phe
- gnomAD rs1311925093
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.26
- CADD 19.50
- PolyPhen-2 0.50
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available