L25M (p.Leu25Met) variant of NPR1 (P16066)
L25M (p.Leu25Met) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- gnomAD 1-153679181-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.29
- CADD 19.50
- PolyPhen-2 0.50
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available