L23M (p.Leu23Met) variant of NPR1 (P16066)
L23M (p.Leu23Met) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L23M (p.Leu23Met) variant details
- p.Leu23Met
- gnomAD 1-153679175-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.19
- CADD 11.00
- PolyPhen-2 0.04
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available