L15P (p.Leu15Pro) variant of NPR1 (P16066)
L15P (p.Leu15Pro) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- ExAC rs765066553
- TOPMed rs765066553
- gnomAD rs765066553
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.28
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available