A8P (p.Ala8Pro) variant of NPR1 (P16066)
A8P (p.Ala8Pro) in NPR1 (P16066) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A8P (p.Ala8Pro) variant details
- p.Ala8Pro
- ExAC rs767857443
- gnomAD rs767857443
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.17
- CADD 9.33
- PolyPhen-2 0.08
- SIFT 0.29
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available