S63T (p.Ser63Thr) variant of NPPB (Natriuretic peptides B)
S63T (p.Ser63Thr) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data, published literature, and structural context.
S63T (p.Ser63Thr) variant details
- p.Ser63Thr
- gnomAD 1-11858415-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0312
- REVEL 0.00
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.80
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available
- Literature evidence available