S55P (p.Ser55Pro) variant of NPPB (Natriuretic peptides B)
S55P (p.Ser55Pro) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
S55P (p.Ser55Pro) variant details
- p.Ser55Pro
- TOPMed rs1203310170
- gnomAD rs1203310170
- Missense
- Variant Prioritization Score for Impact Estimate 0.0823
- REVEL 0.06
- CADD 6.63
- PolyPhen-2 0.04
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available