S26C (p.Ser26Cys) variant of NPPB (Natriuretic peptides B)
S26C (p.Ser26Cys) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S26C (p.Ser26Cys) variant details
- p.Ser26Cys
- TOPMed rs61761993
- gnomAD rs61761993
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.08
- CADD 21.90
- PolyPhen-2 0.98
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available