P66T (p.Pro66Thr) variant of NPPB (Natriuretic peptides B)
P66T (p.Pro66Thr) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
P66T (p.Pro66Thr) variant details
- p.Pro66Thr
- gnomAD 1-11858406-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0527
- REVEL 0.03
- CADD 3.52
- PolyPhen-2 0.17
- SIFT 0.17
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available