P32L (p.Pro32Leu) variant of NPPB (Natriuretic peptides B)
P32L (p.Pro32Leu) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P32L (p.Pro32Leu) variant details
- p.Pro32Leu
- ExAC rs748837558
- gnomAD rs748837558
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.04
- CADD 16.10
- PolyPhen-2 0.06
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available