L67F (p.Leu67Phe) variant of NPPB (Natriuretic peptides B)
L67F (p.Leu67Phe) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L67F (p.Leu67Phe) variant details
- p.Leu67Phe
- ExAC rs750491009
- gnomAD rs750491009
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.02
- CADD 10.40
- PolyPhen-2 0.33
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available