L57M (p.Leu57Met) variant of NPPB (Natriuretic peptides B)
L57M (p.Leu57Met) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
L57M (p.Leu57Met) variant details
- p.Leu57Met
- gnomAD 1-11858433-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.08
- CADD 8.76
- PolyPhen-2 0.16
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available