L29P (p.Leu29Pro) variant of NPPB (Natriuretic peptides B)
L29P (p.Leu29Pro) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L29P (p.Leu29Pro) variant details
- p.Leu29Pro
- ExAC rs768381227
- TOPMed rs768381227
- gnomAD rs768381227
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.19
- CADD 22.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available