L13F (p.Leu13Phe) variant of NPPB (Natriuretic peptides B)
L13F (p.Leu13Phe) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
L13F (p.Leu13Phe) variant details
- p.Leu13Phe
- ExAC rs751286475
- TOPMed rs751286475
- gnomAD rs751286475
- Missense
- Variant Prioritization Score for Impact Estimate 0.0932
- REVEL 0.02
- CADD 13.40
- PolyPhen-2 0.27
- SIFT 0.24
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available