G42R (p.Gly42Arg) variant of NPPB (Natriuretic peptides B)
G42R (p.Gly42Arg) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
G42R (p.Gly42Arg) variant details
- p.Gly42Arg
- ExAC rs758657926
- gnomAD rs758657926
- Missense
- Variant Prioritization Score for Impact Estimate 0.0407
- REVEL 0.01
- CADD 2.31
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available