G42A (p.Gly42Ala) variant of NPPB (Natriuretic peptides B)
G42A (p.Gly42Ala) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
G42A (p.Gly42Ala) variant details
- p.Gly42Ala
- ExAC rs765544521
- gnomAD rs765544521
- Missense
- Variant Prioritization Score for Impact Estimate 0.058
- REVEL 0.05
- CADD 0.65
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available