G23R (p.Gly23Arg) variant of NPPB (Natriuretic peptides B)
G23R (p.Gly23Arg) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G23R (p.Gly23Arg) variant details
- p.Gly23Arg
- ExAC rs760123248
- gnomAD rs760123248
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.05
- CADD 14.50
- PolyPhen-2 0.28
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available