G23A (p.Gly23Ala) variant of NPPB (Natriuretic peptides B)
G23A (p.Gly23Ala) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G23A (p.Gly23Ala) variant details
- p.Gly23Ala
- ExAC rs777336949
- gnomAD rs777336949
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.05
- CADD 16.70
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available