D2N (p.Asp2Asn) variant of NPPB (Natriuretic peptides B)
D2N (p.Asp2Asn) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
D2N (p.Asp2Asn) variant details
- p.Asp2Asn
- ExAC rs753423994
- TOPMed rs753423994
- gnomAD rs753423994
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.08
- CADD 14.60
- PolyPhen-2 0.04
- SIFT 0.06
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available