A10T (p.Ala10Thr) variant of NPPB (Natriuretic peptides B)
A10T (p.Ala10Thr) in NPPB (Natriuretic peptides B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- ExAC rs543699023
- TOPMed rs543699023
- gnomAD rs543699023
- Missense
- Variant Prioritization Score for Impact Estimate 0.0596
- REVEL 0.04
- CADD 4.12
- PolyPhen-2 0.05
- SIFT 0.22
- Most common in the HGDP:BIAKA population (allele frequency 0.023)
- Structural context available