V62L (p.Val62Leu) variant of NPPA (Natriuretic peptides A)
V62L (p.Val62Leu) in NPPA (Natriuretic peptides A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V62L (p.Val62Leu) variant details
- p.Val62Leu
- TOPMed rs1366098026
- gnomAD rs1366098026
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.12
- CADD 9.65
- PolyPhen-2 0.02
- SIFT 0.73
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available