P60T (p.Pro60Thr) variant of NPPA (Natriuretic peptides A)
P60T (p.Pro60Thr) in NPPA (Natriuretic peptides A) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
P60T (p.Pro60Thr) variant details
- p.Pro60Thr
- gnomAD 1-11847383-TGG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.242
- CADD 22.80
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available