P59T (p.Pro59Thr) variant of NPPA (Natriuretic peptides A)
P59T (p.Pro59Thr) in NPPA (Natriuretic peptides A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P59T (p.Pro59Thr) variant details
- p.Pro59Thr
- ExAC rs746809763
- TOPMed rs746809763
- gnomAD rs746809763
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.04
- CADD 8.77
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available