G71A (p.Gly71Ala) variant of NPPA (Natriuretic peptides A)
G71A (p.Gly71Ala) in NPPA (Natriuretic peptides A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G71A (p.Gly71Ala) variant details
- p.Gly71Ala
- gnomAD 1-11847351-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.08
- CADD 10.60
- PolyPhen-2 0.34
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available