V33M (p.Val33Met) variant of NPM1 (Nucleophosmin)
V33M (p.Val33Met) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
V33M (p.Val33Met) variant details
- p.Val33Met
- ExAC rs759228926
- gnomAD rs759228926
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.21
- CADD 25.60
- PolyPhen-2 0.59
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available