S43Y (p.Ser43Tyr) variant of NPM1 (Nucleophosmin)
S43Y (p.Ser43Tyr) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
S43Y (p.Ser43Tyr) variant details
- p.Ser43Tyr
- cosmic curated COSV99744
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.38
- CADD 32.00
- PolyPhen-2 0.76
- SIFT 0.03
- Population evidence available
- Structural context available