S10T (p.Ser10Thr) variant of NPM1 (Nucleophosmin)
S10T (p.Ser10Thr) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S10T (p.Ser10Thr) variant details
- p.Ser10Thr
- gnomAD rs1384214810
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 0.12
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available