S10G (p.Ser10Gly) variant of NPM1 (Nucleophosmin)
S10G (p.Ser10Gly) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S10G (p.Ser10Gly) variant details
- p.Ser10Gly
- TOPMed rs1235542368
- gnomAD rs1235542368
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.11
- CADD 22.80
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available