N35S (p.Asn35Ser) variant of NPM1 (Nucleophosmin)
N35S (p.Asn35Ser) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
N35S (p.Asn35Ser) variant details
- p.Asn35Ser
- ExAC rs766975341
- TOPMed rs766975341
- gnomAD rs766975341
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.16
- CADD 27.30
- PolyPhen-2 0.46
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 5.3e-05)
- Structural context available