M9V (p.Met9Val) variant of NPM1 (Nucleophosmin)
M9V (p.Met9Val) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
M9V (p.Met9Val) variant details
- p.Met9Val
- gnomAD rs925409148
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.20
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available