M7V (p.Met7Val) variant of NPM1 (Nucleophosmin)
M7V (p.Met7Val) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
M7V (p.Met7Val) variant details
- p.Met7Val
- ExAC rs772365842
- TOPMed rs772365842
- gnomAD rs772365842
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.25
- CADD 22.70
- PolyPhen-2 0.05
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available