F19L (p.Phe19Leu) variant of NPM1 (Nucleophosmin)
F19L (p.Phe19Leu) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
F19L (p.Phe19Leu) variant details
- p.Phe19Leu
- Ensembl rs2113141479
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.27
- CADD 29.30
- PolyPhen-2 0.46
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available