D8N (p.Asp8Asn) variant of NPM1 (Nucleophosmin)
D8N (p.Asp8Asn) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
D8N (p.Asp8Asn) variant details
- p.Asp8Asn
- gnomAD rs1389753903
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.12
- CADD 24.10
- PolyPhen-2 0.11
- SIFT 0.06
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available