D26Y (p.Asp26Tyr) variant of NPM1 (Nucleophosmin)
D26Y (p.Asp26Tyr) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
D26Y (p.Asp26Tyr) variant details
- p.Asp26Tyr
- gnomAD 5-171390068-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.561
- REVEL 0.38
- CADD 32.00
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available