D26E (p.Asp26Glu) variant of NPM1 (Nucleophosmin)
D26E (p.Asp26Glu) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
D26E (p.Asp26Glu) variant details
- p.Asp26Glu
- gnomAD 5-171390070-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.15
- CADD 23.50
- PolyPhen-2 0.07
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available