C21F (p.Cys21Phe) variant of NPM1 (Nucleophosmin)
C21F (p.Cys21Phe) in NPM1 (Nucleophosmin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
C21F (p.Cys21Phe) variant details
- p.Cys21Phe
- gnomAD 5-171390054-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.55
- CADD 32.00
- PolyPhen-2 0.68
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available