R40G (p.Arg40Gly) variant of NOS3 (Nitric oxide synthase 3)
R40G (p.Arg40Gly) in NOS3 (Nitric oxide synthase 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
R40G (p.Arg40Gly) variant details
- p.Arg40Gly
- ExAC rs764652925
- TOPMed rs764652925
- gnomAD rs764652925
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.05
- CADD 6.27
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available